Mediators of Blood-Brain Barrier Dysfunction and Formation of Vasogenic Brain Edema
نویسندگان
چکیده
منابع مشابه
Mediators of blood-brain barrier dysfunction and formation of vasogenic brain edema.
The characteristics and mechanisms enabling the blood-brain barrier (BBB) to maintain the milieu of the brain have been reviewed in detail elsewhere (Banks and Kastin, 1987; Bradbury, 1985; Crone, 1986a, 1987; Cornford, 1985; Davson, 1976; Er misch et aI. , 1985; Fenstermacher, 1985; Gjedde, 1983; Goldstein and Betz, 1986; Meisenberg and Simmons, 1983; Oldendorf, 1974; Pardridge, 1983; Rapopor...
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Brain edema (BE) research lacks quantitative regional methods. We modified the method of Pappius and McCann (1969), who used radioactive iodinated P serum albumin (R1SA) as a label for vasogenic BE fluid. To correct for intravascular plasma volume we used Cr^ labelled red blood cells and calculated equivalent extravascular plasma volume (EVPV). The modified RISA method was compared with a stand...
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Background and purpose: Traumatic brain injury (TBI) is one of the most complex diseases of the central nervous system (CNS). Nesfatin is an 82-amino acid effective polypeptide in CNS. In this study, we investigated the role of nesfatin in neuron protection in the process of diffuse concussion in rats and also its effect on the level of matrix metalloproteinase-9. Materials and methods: In thi...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 1988
ISSN: 0271-678X,1559-7016
DOI: 10.1038/jcbfm.1988.109